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Tetrahydrofuran for HPLC

Tetrahydrofuran for HPLC

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Initially, Tetrahydrofuran was used for High-performance liquid chromatography as a mobile phase solvent. Its strength is similar to that of acetonitrile, infact, slightly higher than it. As it is an ether, it is easily miscible in water, finding application in the reverse phase of HPLC. This compound renders additional options to have ternary mixes, during incapability of combination of water and methanol or water with acetonitrile for producing a fine tuned separation. Moreover, in analytical chemistry it finds application for separating, quantifying and identifying each component in a particular mixture.

Technical Specifications of Tetrahydrofuran for HPLC & Spectroscopy

  • C4H8O M.W. 72.11 500 ml
  • Assay(GC) ³ 99.8% 1 Ltr
  • Maximum Limits of Impurities : 2.5 Ltr
  • Non-volatile matter 0.0001%
  • Peroxides 0.01%
  • Acidity(CH3COOH) 0.001%
  • Water 0.05%
  • Maximum absorbance in a 1.0 cm cell against water at:
  • 230 nm 1.00
  • 240 nm 0.40
  • 250 nm 0.20
  • 270 nm 0.10
  • 300 nm 0.02
  • 350 nm 0.01
  • Physical Data
  • Boiling point(760mm Hg) 66oC
  • Refractive index(n 20o/D) 1.407
  • Viscosity(20oC) 0.55cP
  • Density(d 20o/4) 0.889
  • Flash point -180C
  • Polarity index(P1) 4.2
  • Selectivity group III
  • Cas No: 109-99-9 Un No. 3.1/2056 TARIFF : 2832 11 00
  • R : 11-19-36/37 S : 16-29-33 F : 1